Channel 143100-KCNQ

General data

• ICG id: 1219
• ModelDB id: 143100
• Reference: Fujita T, Fukai T, Kitano K (2012): Influences of membrane properties on phase response curve and synchronization stability in a model globus pallidus neuron.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, globus pallidus (GP)
• Neuron Region: single compartment
• Neuron Type: globus pallidus (GP) neuron
• Runtime Q: Q1 (fast)
• Subtype: KCNQ

Metadata generic

• Age: 16-21 days
• Authors: K Kitano
• Comments: Kcnq potassium channel for gpe neuron, modeled by gunay et al. (2008), implemented in neuron by kitano, 2011. No model db ancestors. Originally, the kinetics were fit to data in gamper et al. (2003), prole & marrion (2004) (info from gunay paper). Modeling study based on a previous paper, with experiments and multicompartmental modeling (gunay et al. 2008). Animal model comes from this previous paper.
• Runtime: 7.304
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp