Channel 112546-kdrca1

General data

• ICG id: 115
• ModelDB id: 112546
• Reference: Shah MM, Migliore M, Valencia I, Cooper EC, Brown DA (2008): Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: 5-6 weeks old
• Authors: M Migliore
• Comments: K-dr channel originally from migliore et al. (1999). Morphology used in this model is from migliore et al. (2005), but no references are given for channel kinetics. This file appears to be taken from migliore et al. (2005), model no. 55035, with no changes between the files. This paper contains experimental results and modeling based on the model in migliore et al. (2005) and others. The animal model info here is from the experimental methods. The morphology used in the model was the same as in migliore et al. (2005), slightly older rats.
• Runtime: 7.562
• Temperature: Model has temperature dependence, with q10 set to 1.0 and original kinetics at 24 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp