Channel 139653-K_Pst

General data

• ICG id: 1089
• ModelDB id: 139653
• Reference: Hay E, Hill S, Schurmann F, Markram H, Segev I (2011): Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: persistent

Metadata generic

• Age: P36
• Authors: E Hay
• Comments: The persistent component of the k current for l5 neocortical pyramidal neurons from young rats, from korngreen and sakmann (2000), model no. 3289, shifted -10 mv to correct for junction potential. Besides shift, kinetics appear to be the same, although the mod files may have been written independently. Modeling study, that is constrained by experimental data (animal model here) (see le be et al. 2007). Channel kinetics come from various sources.
• Runtime: 7.644
• Temperature: Model has temperature dependence. Original temperature is 21 deg C. Here, qt is set to 2.3, to adjust kinetics for simulations at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp