Channel 114685-HCN

General data

• ICG id: 241
• ModelDB id: 114685
• Reference: Johnson MD, McIntyre CC (2008): Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation.

Metadata classes

• Animal Model: rat, monkey, macaque
• Brain Area: external globus pallidus (GPe), basal ganglia, internal globus pallidus (GPi), globus pallidus (GP), entopeduncular nucleus (EP) -- basal ganglia
• Neuron Region: soma, dendrites
• Runtime Q: Q1 (fast)
• Subtype: h

Metadata generic

• Authors: A Gillies, MD Johnson
• Comments: Potassium ih channel for gpi neuron model. Hcn1 and hcn2, from huguenard & mccormick (1992) and mccormick and paper (1990). Taken from gillies and willshaw (2006), model no. 74298, with several changes. Modeling study that uses morphology and other data from monkey, and other physiology information from rat ep, the gp analogue.
• Runtime: 12.881
• Temperature: Kinetics modified for simulations at 36 deg C, but no standard temperature dependence formulation.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp