Channel 97860-sk_dop

General data

• ICG id: 2571
• ModelDB id: 97860
• Reference: Chan CS, Guzman JN, Ilijic E, Mercer JN, Rick C, Tkatch T, Meredith GE, Surmeier DJ (2007): 'Rejuvenation' protects neurons in mouse models of Parkinson's disease.

Metadata classes

• Animal Model: mouse
• Brain Area: basal ganglia, substantia nigra pars compacta (SNc)
• Neuron Region: single compartment
• Neuron Type: dopaminergic
• Runtime Q: Q3
• Subtype: SK

Metadata generic

• Age: adult (<P28), juvenile (<P21)
• Authors: J Held
• Comments: Sk-type calcium-dependent potassium channel. Based on kinetics from ahp channel model in migliore et al. (1995), model no. 3263, with modified gbar value, but no apparent changes to kinetics. Animal model comes from experiments in paper. Channel kinetics are mostly from unspecified sources.
• Runtime: 75.36
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp