Channel 64195-na

General data

• ICG id: 2187
• ModelDB id: 64195
• Reference: Kole MH, Hallermann S, Stuart GJ (2006): Single Ih channels in pyramidal neuron dendrites: properties, distribution, and impact on action potential output.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Region: soma, dendrites, axon
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Age: 28-70 days
• Authors: Z Mainen, S Hallermann
• Comments: Sodium channel, h-h kinetics, fit to data from huguenard et al. (1988) and hamill et al (1991). Written by z mainen 1994, modified by s hallermann (2006) to correct error in trap0 function. Taken from schaefer et al. (2003), model no. 83344, with slightly different implementation but no apparent changes to kinetics. Experimental data to get info for ih currents, model very similar to ancestor. The animal model info here is from the experimental procedures.
• Runtime: 4.513
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C. Simulation temperature was 35 deg C, experimental procedures at 33-35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp